Sensorimotor and Physiological Markers of Fragile X-Associated Tremor/Ataxia Syndrome (FXTAS)
Fragile X-associated tremor/ataxia syndrome (FXTAS) is the most common known single-gene form of ataxia in the aging population. Affected individuals have areas of damage in the cerebellum, the part of the brain that controls movement causing problems with movement and thinking ability. FXTAS progresses rapidly, but it often is initially misdiagnosed, and no effective treatments currently are available. This project is working towards determining specific markers of FXTAS.